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NIRANJANA J P

PhD Student

NIRANJANA J P

REG NO: 20-52-02

RESEARCH AREA: STUDIES ON SILK AND SILK BASED NANOCOMPOSITES


Google Scholar Profile: https://scholar.google.com/citations?user=nmM-zxcAAAAJ&hl=en

Linkedin Profile: https://www.linkedin.com/in/niranjana-jayaprakash-b89137171/


RESEARCH DOMAINS

· Silk based materials

· Natural polymers

· Nanocomposites

· Polymer processing

· Structure-property relationship

· Biomedical


PUBLISHED PAPERS:

1) Niranjana JayaPrakash, Prathamesh Parshuram Mane, Suchi Mercy George, and Balasubramanian Kandasubramanian. "Silk fibroin as an immobilization matrix for sensing applications." ACS Biomaterials Science & Engineering 7, no. 6 (2021): 2015-2042.

DOI:10.1021/acsbiomaterials.1c00080





ABSTRACT:

The development of flexible, biocompatible, and environment-friendly sensors has attracted a significant amount of scientific interest for the past few decades. Among all the natural materials, silk fibroin (SF), due to its tunable biodegradability, biocompatibility, ease of processing, presence of functional groups, and controllable dimensions, has opened up opportunities for immobilizing multitudinous biomolecules and conformability to the skin, among other attractive opportunities. The silk fibroins also offer good physical properties, such as superior toughness and tensile strength. The sensors made of SF as an immobilization matrix have demonstrated excellent analytical performance, sensing even at low concentrations. The significant advantage of silk fibroins is the presence of functional groups along with a controllable conformation transition that enables immobilization of receptor molecules using silk fibroins as an immobilization matrix enables us to entrap the receptor molecules without using any chemical reagents. This review encompasses a detailed discussion on sensors, the advantages of using silk fibroins as an immobilization matrix for various receptors, their applications, and the future research scope in this state-of-the-art technology based upon the explorable applications for silk fibroin-based sensors.


2) Niranjana JayaPrakash, and Balasubramanian Kandasubramanian. "Nanocomposites of MXene for industrial applications." Journal of Alloys and Compounds 862 (2021): 158547.

DOI:https://doi.org/10.1016/j.jallcom.2020.158547





ABSTRACT:

The two-dimensional (2D) materials are often mentioned as the wonder materials that will lead this era of science. They are vouched as the perfect solution to many of the world's problems. The 2D carbides, nitrides, and carbonitrides of transition metals, known by the name MXenes, contributes one amongst the largest 2D material family. MXenes efficaciously combine with polymers, ceramics, metals, and nanoparticles to form composites elucidated enhanced performance. Their unique chemical and physical properties render them excellent optical, electronic, structural, mechanical, and thermal properties. They have already found their place in several applications such as energy storage (910 mA h g−1 capacity at 100 mA g−1), sensors, electromagnetic interference (EMI) shielding (SE ≈ 57 dB at 0.009 mm thickness), catalysis, biomedical (imaging, drug delivery, GBR), tribology (98.4% reduction in COF), environmental, and so on. Their scalable production technique opens them up to a great variety of industrial applications. This article discusses the structure, synthesis, properties, and several industrially important applications of MXene and MXene based composites.


3. Nikhil Avinash Patil, Prakash Macchindra Gore, Niranjana Jaya Prakash, PremikaGovindaraj, Ramdayal Yadav, Vivek Verma, DhivyaShanmugarajan, Shivanand Patil, Abhay Kore, and Balasubramanian Kandasubramanian. "Needleless electrospun phytochemicals encapsulated nanofibre based 3-ply biodegradable mask for combating COVID-19 pandemic." Chemical Engineering Journal 416 (2021): 129152.

DOI:https://doi.org/10.1016/j.cej.2021.129152





ABSTRACT:

The emergence of COVID-19 pandemic has severely affected human health and world economies. According to WHO guidelines, continuous use of face mask is mandatory for personal protection for restricting the spread of bacteria and virus. Here, we report a 3-ply cotton-PLA-cotton layered biodegradable face-mask containing encapsulated phytochemicals in the inner-filtration layer. The nano-fibrous PLA filtration layer was fabricated using needleless electrospinning of PLA & phytochemical-based herbal-extracts. This 3-layred face mask exhibits enhanced air permeability with a differential pressure of 35.78 Pa/cm2 and superior bacterial filtration efficiency of 97.9% compared to conventional face masks. Close-packed mesh structure of the nano-fibrous mat results in effective adsorption of particulate matter, aerosol particles, and bacterial targets deep inside the filtration layer. The outer hydrophobic layer of mask exhibited effective blood splash resistance up to a distance of 30 cm, ensuring its utilization for medical practices. Computational analysis of constituent phytochemicals using the LibDock algorithm predicted inhibitory activity of chemicals against the protein structured bacterial sites. The computational analysis projected superior performance of phytochemicals considering the presence of stearic acid, oleic acid, linoleic acid, and Arachidic acid exhibiting structural complementarity to inhibit targeted bacterial interface. Natural cotton fibers and PLA bio-polymer demonstrated promising biodegradable characteristics in the presence of in-house cow-dung based biodegradation slurry. Addition of jaggery to the slurry elevated the biodegradation performance, resulting in increment of change of weight from 07% to 12%. The improved performance was attributed to the increased sucrose content in biodegradation slurry, elevating the bacterial growth in the slurry. An innovative face mask has shown promising results for utilization in day-to-day life and medical frontline workers, considering the post-pandemic environmental impacts.


4. FuharDixit,, Karl Zimmermann, Rahul Dutta, Niranjana Jaya Prakash, Benoit Barbeau, MadjidMohseni, and Balasubramanian Kandasubramanian. "Application of MXenes for water treatment and energy-efficient desalination: A review." Journal of Hazardous Materials 423 (2022): 127050.

DOI :https://doi.org/10.1016/j.jhazmat.2021.127050





Abstract

MXenes are a new type of two-dimensional (2D) material which are rapidly gaining traction for a range of environmental, chemical and medical applications. MXenes and MXene-composites exhibit high surface area, superlative chemical stability, thermal conductivity, hydrophilicity and are environmentally compatible. Consequently, MXenes have been successfully employed for hydrogen storage, semiconductor manufacture and lithium ion batteries. In recent years, MXenes have been utilized in numerous environmental applications for treating contaminated surface waters, ground and industrial/ municipal wastewaters and for desalination, often outperforming conventional materials in each field. MXene-composites can adsorb multiple organic and inorganic contaminants, and undergo Faradaic capacitive deionization (CDI) when utilized for electrochemical applications. This approach allows for a significant decrease in the energy demand by overcoming the concentration polarization limitation of conventional CDI electrodes, offering a solution for low-energy desalination of brackish waters. This article presents a state-of-the-art review on water treatment and desalination applications of MXenes and MXene-composites. An investigation into the kinetics and isotherms is presented, as well as the impact of water constituents and operating conditions are also discussed. The applications of MXenes for CDI, pervaporation desalination and solar thermal desalination are also examined based on the reviewed literature. The effects of the water composition and operational protocols on the regeneration efficacy and long-term usage are also highlighted.


5. NeelaambhigaiMayilswamy,, Niranjana Jaya Prakash, and Balasubramanian Kandasubramanian. "Design and fabrication of biodegradable electrospun nanofibers loaded with biocidal agents." International Journal of Polymeric Materials and Polymeric Biomaterials (2022): 1-27.

DOI:https://doi.org/10.1080/00914037.2021.2021905





Abstract:

Electrospinning, a versatile nanofiber processing technique, has acquired considerable attention over conventional nanofiber fabrication methods owing to its inherent advantages, such as reasonable control over fiber dimensions, scalability, process convenience, and applicability towards an extensive array of materials. Electrospun biodegradable polymer nanofibers based on Poly(vinyl alcohol) (PVA), Poly(β-hydroxybutyrate-β-hydroxyvalerate) (PHBV), Poly(lactic-co-glycolic acid) (PLGA), Polycaprolactone (PCL), and Polylactic acid (PLA) incorporating various biocidal agents for biomedical applications which embodies tissue engineering scaffolds, wound dressing and drug delivery would be addressed here. This review also provides an insight into computational studies of polymers loaded with nanoparticles to examine the interaction studies between them


NIRANJANA J P

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